Global circumferential left ventricular strain impairment in hypertrophic cardiomyopathy: comparison to left ventricular hypertrophy and late gadolinium enhancement
نویسندگان
چکیده
Results HCM patients (50±18 years, 65% men) had normal LVEDV (149±46mL, p=0.24), LVESV (52±24mL, p=0.78) and LVEF (65±11%, p=0.38). LV mass (198±69g, p<0.001) and LV mass index (108±37g/m2 p=0.002) were significantly increased, resulting in decreased LV mass/LV volume ratio (1.40±0.54, p=0.005) in HCM compared to controls. Median maximal wall thickness was 19.6 (14.4 to 32.3mm). In HCM, LGE was present in 32/40 (80%) and mean LGE mass was 4.31±4.94g. Ecc was significantly impaired in HCM patients (-8.82 ±0.32 vs. -15.54±2.54%, p<0.0001) Ecc impairment was significantly associated with increased LV mass index (r=0.51, p=0.0009), LV mass/ LV volume ratio (r=0.67,p<0.0001) and LV maximal wall thickness (r=0.51, p=0.008). Moreover, Ecc impairment was associated with increased LGE mass (r=0.39, p=0.01).
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